Open AccessLow dose multidetector computed tomography in localizing the transition zone of Hirschsprung’s Disease: A novel study
Author(s) -
Gehan S. Seifeldein,
Nagwa M. Omar,
Nagla H. Abu Faddan,
Omar Abd Elraheem
Publication year - 2016
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2016.06.019
Subject(s) - medicine , computed tomography , pathological , radiology , multidetector computed tomography , sigmoid colon , nuclear medicine , hirschsprung's disease , surgical planning , disease , surgery , rectum , pathology
Objectives: The objectives of this study were the evaluation of low dose multidetector computed tomography (MDCT) in localizing the site of the transition zone (TZ) of Hirschsprung’s Disease (HD) for preoperative planning.Patients and methods: Twenty-two infants were recruited from pediatric and surgical clinics in Assiut University Hospital and Sohag University Hospital. The recruited patients were sedated before examination. Examinations were done using 64-rows MDCT. Each MDCT examination was reviewed to determine the location and length of the TZ and compared with operative and pathological results. Results were analyzed by chi square test and interobserver agreement using Kappa test. P < 0.05 was considered statistically significant.Results: According to operative and pathological data, the site of the TZ: 17 (77.27%) were of short-segment disease (rectosigmoid HD), 2 (9%) were of long segment (above sigmoid colon), and 3 (13.63%) were of ultrashort segment. A correct diagnosis of TZ by MDCT was made in 19 out of 22 with 82.4% sensitivity and 80% specificity. The site of TZ was concordant in 17. Results yielded a moderate strength of inter-observer agreement in localizing the site of TZ (k = 0.546) and ( P= 0.009).Conclusion: Low-dose MDCT has a good role in localizing the site of TZ of HD in infants