Open AccessAndrogen insensitivity syndrome with inguinal testes: MRI diagnosis
Author(s) -
Ahmed Samy El-Agwany
Publication year - 2016
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2016.01.004
Subject(s) - complete androgen insensitivity syndrome , androgen insensitivity syndrome , medicine , inguinal canal , primary amenorrhea , male pseudohermaphroditism , androgen receptor , gynecology , amenorrhea , external genitalia , androgen , urology , anatomy , endocrinology , hormone , radiology , biology , pregnancy , genetics , prostate cancer , cancer , inguinal hernia , hernia
Complete androgen insensitivity syndrome is an X-linked recessive androgen receptor disorder. It is characterized by female phenotype with XY karyotype. Patients have normal female external genitalia and absent Mullerian duct derivatives with the presence of testes. It occurs in up to 5 every 100,000 males. Imaging is important to diagnose and to localize gonads prior to surgical treatment. We report a case of 20-year-old female who presented with primary amenorrhea to our department. Investigations revealed the absence of female internal genitalia and the presence of testes on MRI in the inguinal canal under the skin. Gonadectomy was done and she was put on female hormone replacement therapy