Open AccessRole of diffusion weighted imaging and dynamic contrast enhanced magnetic resonance imaging in breast tumors
Author(s) -
Magda Ali Hany El Bakry,
Amina Sultan,
Nahed Abd Elgaber El-Tokhy,
Tamer Fady Yossif,
Carmen Ali Ahmed Ali
Publication year - 2015
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2015.04.008
Subject(s) - medicine , magnetic resonance imaging , diffusion mri , breast mri , radiology , dynamic contrast , differential diagnosis , dynamic contrast enhanced mri , nuclear medicine , diffusion weighted magnetic resonance imaging , breast cancer , mammography , pathology , cancer
Purpose: To evaluate the role of diffusion weighted imaging and dynamic contrast enhanced magnetic resonance imaging in characterization of breast tumors and comparing the results with the histological finding.Patients and methods: From January 2011 to January 2015, 71 patients with 74 suspicious breast lesions had performed breast DCE-MRI combined with DWI and the results were compared with the histopathological examination which was used as the standard diagnostic method.Results: The study included 71 patients with 74 suspicious breast lesions, there were 38 benign lesions ((51.35%) and 36 malignant lesions (48.65%)).DCE-MRI proved to have a sensitivity of 91.7%, and a specificity of 84.2%. ADC cutoff value to differentiate between benign and malignant lesions was 1.32 × 103 mm2/s (P < 0.001). The diffusion weighted MRI proved to have a sensitivity of 94.4%, and a specificity of 92.1%.The combined MRI protocol of DCEMRI and DWI proved to increase the sensitivity and specificity of breast MRI.Conclusion: DWI had a higher sensitivity and specificity than DCE-MRI. The combined MRI protocol of DCEMRI and DWI proved to increase sensitivity and specificity of MRI in diagnosis and differential diagnosis of breast lesions