Open AccessCeliac disease: Do not miss that diagnosis!
Author(s) -
Mohamed Eid,
Ahmed Mohamed Abougabal,
Ahmed Zeid
Publication year - 2013
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2013.09.010
Subject(s) - medicine , tissue transglutaminase , biopsy , radiology , gastroenterology , lymph , duodenum , serology , mesenteric lymph nodes , intussusception (medical disorder) , jejunum , thickening , pathology , antibody , spleen , biochemistry , chemistry , polymer science , immunology , enzyme
AbstractBackgroundCeliac disease (CD) is a chronic autoimmune disorder induced in genetically susceptible individuals after ingestion of gluten proteinsAim of the workTo highlight the utility of abdominal CT/enterography in diagnosis of CD.Subjects & methodsThis retrospective study included 12 patients presented to our institute during the period from May 2011 till April 2013 with vague abdominal symptoms, performed abdominal CT/enterography. The final diagnosis was reached in all patients through upper GI endoscopy, duodenal biopsy and serological tests including anti-tissue transglutaminase and anti-endomysial antibodies.ResultsThe sensitivity of different CT signs was calculated against the diagnostic standard of reference (biopsy & serology). The jejuno-ileal fold reversal pattern was detected in 100% of patients. Other findings included (in descending order): Enlarged mesenteric lymph nodes in eight patients (66.5%); jejunal wall thickening, dilated jejunal loops, and cavitating lymph nodes in six patients (50%); dilated ileal loops in four patients (33%); ileal wall thickening in three patients (25%); thickened duodenum, and small bowel intussusception in two patients (16.5%).ConclusionsCT is an efficient imaging tool in diagnosis of CD. The jejuno-ileal fold reversal pattern is highly in favor of the diagnosis of CD