Open AccessEvaluation of median nerve in children with type1 diabetes using ultrasonographic imaging and electrophysiology
Author(s) -
Rania Refaat,
Abeer Maghawry Abdelhameed,
Nancy Samir Elbarbary,
Nesrine A Mohamed
Publication year - 2013
Publication title -
the egyptian journal of radiology and nuclear medicine /the egyptian journal of radiology and nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.19
H-Index - 13
eISSN - 2090-4762
pISSN - 0378-603X
DOI - 10.1016/j.ejrnm.2013.06.002
Subject(s) - medicine , median nerve , carpal tunnel syndrome , diabetes mellitus , nerve conduction velocity , diabetic neuropathy , carpal tunnel , motor nerve , nerve conduction , electrophysiology , peripheral neuropathy , complication , surgery , anatomy , endocrinology
BackgroundDiabetic peripheral neuropathy (DPN) is a worldwide costly complication of diabetes.ObjectiveTo evaluate the relationship between the sonographically measured cross-sectional area (CSA) of the median nerve and nerve conduction study (NCS) in children with type1 diabetes (T1DM) complaining of DPN.Material and methodsForty children with T1DM and 20 age-matched healthy subjects were enrolled in this study. The diabetic children were divided into 2 groups (without and with DPN). All participants underwent NCS and sonographic measurement of CSA for the median nerve in the carpal tunnel.ResultsThe CSA of the median nerve in children with DPN was higher than that in the control subjects yet with no significant difference with that of children without DPN. The increased median nerve CSA in the carpal tunnel was considerably correlated with the median nerve motor latency and duration of diabetes, nevertheless, with no correlation with median nerve motor conduction velocity (MNCV).ConclusionSonographic measurement of CSA of the median nerve in the carpal tunnel serves as a good discriminator for diabetic children from healthy individuals. Moreover, it has significant positive correlation with duration of disease and the nerve motor latency