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Health related quality of life of patients with refractory angina before and one year after enrolment onto a refractory angina program
Author(s) -
Moore R.K.,
Groves D.,
Bateson S.,
Barlow P.,
Hammond C.,
Leach A.A.,
Chester M.R.
Publication year - 2005
Publication title -
european journal of pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.305
H-Index - 109
eISSN - 1532-2149
pISSN - 1090-3801
DOI - 10.1016/j.ejpain.2004.07.013
Subject(s) - refractory (planetary science) , angina , medicine , quality of life (healthcare) , cardiology , physical therapy , metallurgy , materials science , nursing , myocardial infarction
Objective : This study was designed to assess the impact of a refractory angina programme on the health related quality of life for patients with chronic refractory angina (CRA) one year following enrolment. Design : A one year prospective audit. Setting : Specialist refractory angina clinic at a tertiary cardiac referral centre. Patients : 69 consecutive refractory angina patients referred to a regional refractory angina centre from 1/03/2001 to 1/09/2002. Interventions : Pain treatment algorithm in accordance with the recommendations of the national refractory angina guideline committee. Main outcome measures : Improvements in quality of life indices were assessed using Seattle angina questionnaire (SAQ), and short form‐12 (SF‐12) with changes in mood determined using the hospital anxiety and depression (HAD) questionnaire. Results : All dimensions of the SF‐12 and SAQ were superior at one year with significant improvement seen with the mental component of SF‐12 ( p = 0.023), and four of the five SAQ domains, angina stability ( p = 0.028), angina frequency ( p = 0.02), treatment satisfaction ( p = 0.001) and quality of life ( p < 0.001). All the significant changes within the SAQ domains were large enough to be considered clinically relevant. At one year the anxiety and depression domains were significantly improved from baseline ( p = 0.015, 0.018) with clinical anxiety levels falling significantly from 55% to 40%, a relative reduction of 28% ( p = 0.008). Conclusions : Implementation of the national refractory angina guidelines in a prospective study of 69 consecutive CRA patients significantly improved health related quality of life status at one year.