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Effects of functional electrical stimulation on quality of life and emotional stress in patients with chronic heart failure secondary to ischaemic or idiopathic dilated cardiomyopathy: A randomised, placebo‐controlled trial
Author(s) -
Karavidas Apostolos,
Parissis John,
Arapi Sophia,
Farmakis Dimitrios,
Korres Dimitrios,
Nikolaou Maria,
Fotiadis John,
Potamitis Nikolaos,
Driva Xenia,
Paraskevaidis Ioannis,
Matsakas Evaggelos,
Filippatos Gerasimos,
Kremastinos Dimitrios T.
Publication year - 2008
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1016/j.ejheart.2008.05.014
Subject(s) - medicine , ejection fraction , heart failure , placebo , quality of life (healthcare) , functional electrical stimulation , cardiology , depression (economics) , dilated cardiomyopathy , natriuretic peptide , randomized controlled trial , cardiomyopathy , physical therapy , beck depression inventory , stimulation , anxiety , alternative medicine , nursing , pathology , economics , macroeconomics , psychiatry
Objective Functional electrical stimulation (FES) improves exercise capacity and endothelial function in chronic heart failure (CHF) patients. This study evaluates the impact of FES on quality of life and emotional stress in patients with moderate to severe CHF. Methods Thirty patients with stable CHF (24 men; NYHA class II–III; left ventricular ejection fraction <35%) were randomly assigned (2:1) to a 6‐week FES training program ( n =20) or placebo ( n =10). Questionnaires addressing quality of life [Kansas City Cardiomyopathy Questionnaire (KCCQ), functional and overall], and emotional stress [Zung self‐rating depression scale (SDS), Beck Depression Inventory (BDI)], as well as plasma B‐type natriuretic peptide (BNP) and 6‐min walking distance test (6MWT) were assessed at baseline and after completion of training protocol. Results A significant improvement in KCCQ functional ( F =76.666, p <0.001), KCCQ overall ( F = 41.508, p <0.001), BDI ( F = 17.768, p <0.001) and Zung SDS ( F = 27.098, p <0.001) was observed in the FES group compared to placebo. Patients in the FES group had also a significant increase in 6MWT ( F = 19.413, p <0.001) and a trend towards reduction in plasma BNP ( F = 4.252, p =0.053) compared to placebo. Conclusion FES seems to have a beneficial effect on quality of life, exercise capacity and emotional stress in patients with moderate to severe CHF.