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Tako‐Tsubo‐like syndrome during anaphylactic reaction
Author(s) -
Vultaggio Alessandra,
Matucci Andrea,
Del Pace Stefano,
Simonetti Ignazio,
Parronchi Paola,
Rossi Oliviero,
Maggi Enrico,
Gensini Gianfranco,
Romagnani Sergio
Publication year - 2007
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1016/j.ejheart.2006.05.011
Subject(s) - medicine , cardiology , anaphylaxis , chest pain , cardiomyopathy , angioedema , heart failure , acute coronary syndrome , allergy , myocardial infarction , immunology
Tako‐Tsubo's syndrome (apical ballooning or broken heart syndrome) is a reversible left ventricular dysfunction due to apical asynergy that occurs typically after sudden emotional stress in a subject without coronary disease. It is characterized by acute onset of chest pain or dyspnoea or both and is associated with electrocardiographic changes such as ST segment elevation and/or T wave inversion. Myocardial biomarkers may be normal or slightly elevated. Anaphylaxis is a severe, life‐threatening, generalized hypersensitivity reaction, most often starting with urticaria and/or angioedema, that may involve cardiovascular and respiratory systems. Cardiovascular symptoms, including hypotension, cardiac arrhythmia and chest pain, are presumably linked to cardiac mast cell mediator release. We describe the case of a young woman who experienced a profound reversible cardiomyopathy with typical features of Tako‐Tsubo's syndrome during an anaphylactic reaction.