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Coronary sinus thermography in idiopathic dilated cardiomyopathy: Correlation with systemic inflammation and left ventricular contractility
Author(s) -
Toutouzas Konstantinos,
Stougiannos Pavlos,
Drakopoulou Maria,
Mitropoulos John,
Bosinakou Eirini,
Markou Virginia,
Latsios George,
Karabelas Ioannis,
Stefanadi Elli,
Stefanadis Christodoulos
Publication year - 2007
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1016/j.ejheart.2006.04.002
Subject(s) - medicine , coronary sinus , dilated cardiomyopathy , cardiology , ejection fraction , heart failure , contractility , cardiomyopathy , thermography , physics , infrared , optics
Background Previous studies have demonstrated that patients with heart failure have increased myocardial heat production. Coronary sinus (CS) thermography is a new method for the evaluation of left ventricular heat production. Aims We investigated whether the CS blood temperature is increased in patients with idiopathic dilated cardiomyopathy (DCM) compared to a control group and whether the CS blood temperature correlates with ejection fraction and systemic inflammatory activation. Methods and results We included 25 patients with DCM and 22 healthy subjects. Temperature measurements were performed using a new thermography catheter. Temperature difference (Δ T ) was defined as the difference between the CS and RA blood temperature. The CRP levels were also measured. Δ T was significantly greater in patients with DCM compared to the controls (0.25±0.09 vs 0.14±0.07 °C, p <0.01). Δ T and EF were inversely correlated in patients with DCM ( R =0.43). We categorized patients with DCM into two groups using a CRP cut‐off value of ≤1 mg/dL. Δ T in patients with high CRP was less (0.21±0.06 °C) compared to patients with low CRP (0.30±0.08 °C, p =0.01). Conclusions In patients with DCM increased heat production from the myocardium, as estimated from the coronary sinus blood temperature, was demonstrated, interestingly there was no correlation with systemic inflammatory activation.