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Incident atrial fibrillation and mortality in older adults with heart failure
Author(s) -
Ahmed Ali,
Perry Gilbert J.
Publication year - 2005
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1016/j.ejheart.2004.12.004
Subject(s) - medicine , atrial fibrillation , hazard ratio , confidence interval , heart failure , proportional hazards model , cardiology
Abstract We studied 944 hospitalized heart failure patients 65 years and older to examine the impact of incident atrial fibrillation on mortality. Patients were categorized into four groups based on past medical history and admission electrocardiogram: (1) no (neither past nor current), (2) incident (newly diagnosed), (3) past and (4) chronic (past and current) atrial fibrillation. The primary outcome was 4‐year all‐cause mortality. Bivariate and multivariable Cox proportion hazards analyses were used to determine risk of all‐cause mortality. In the multivariable model, we adjusted for various demographic and clinical covariates. Compared with patients who never had atrial fibrillation, those with incident atrial fibrillation had a 57% higher risk of death (unadjusted hazard ratio, 1.57; 95% confidence interval, 1.22–2.03). After adjustment for other covariates the association remained unchanged (adjusted hazard ratio, 1.41; 95% confidence interval, 1.08–1.83). Past or chronic atrial fibrillation was not associated with increased risk of death.