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Six years follow‐up of an implanted SvO 2 sensor in the right ventricle
Author(s) -
Kjellström Barbro,
Linde Cecilia,
Bennett Tom,
Ohlsson Åke,
Ryden Lars
Publication year - 2004
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1016/j.ejheart.2003.12.021
Subject(s) - medicine , ventricle , cardiology , oxygen saturation , heart failure , oxygen , chemistry , organic chemistry
. Mixed venous oxygen saturation (SvO 2 ) is a standard invasive measure used in the management of congestive heart failure patients. The reliability of a long‐term SvO 2 sensor remains unproven. Methods. Nine patients (NYHA Class I/II, n =2/7) were implanted with a dual chamber pacemaker modified to utilize a right ventricular SvO 2 lead (Medtronic Inc., Models 8007/4327A IPG/Lead). Invasive studies compared sensor SvO 2 to reference (Optical Swan–Ganz catheter) at 0, 3 and 9 months. Symptom limited tests (Bike max ) with metabolic assessment and arterial oxygen saturation measurements performed 1–7 days, 3.5 and 9.5 months post‐implant allowed for cardiac output calculations. Long‐term sensor performance was confirmed by submaximal tests, Bike subm in years 1–3, and Walk in‐place every 6 months for the duration of follow‐up. Results. Sensor SvO 2 readings were stable over time when compared to the Swan–Ganz Catheter. Non‐invasive CO measured during Bike max was in normal ranges for this patient population, 3.7±0.9 l/min at rest and 8.4±2.2 l/min at peak‐exercise. Resting SvO 2 values from Bike subm and Walk in‐place did not change significantly over time ( P 0.1 vs. 1 year) and neither did the change from rest to peak exercise during Bike subm ( P 0.05 vs. 1 year) or Walk in‐place ( P 0.05 vs. 4 year). Conclusion. While limited in size, this small pilot study suggests that long‐term monitoring of SvO 2 by implanted devices may be feasible. The clinical value remains to be proven in future studies.