Open AccessHuman papillomavirus positive oropharyngeal cancer: The general information
Author(s) -
Ömer Tarık Selçuk
Publication year - 2016
Publication title -
egyptian journal of ear nose throat and allied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 8
eISSN - 2090-3405
pISSN - 2090-0740
DOI - 10.1016/j.ejenta.2016.07.007
Subject(s) - medicine , human papilloma virus , head and neck cancer , human papillomavirus , oncology , incidence (geometry) , cancer , squamous cell cancer , head and neck , cervical cancer , surgery , physics , optics
Oropharyngeal squamous cell cancer (OPSCC) and especially Human papilloma virus positive (HPV+) OPSCC incidence is increasing worldwide over the last decades while the incidence of overall head and neck squamous cancers has declined in developed countries. HPV+OPSCC has favorable prognosis and is seen in younger patients with lower exposure to tobacco and alcohol. This review will summarize our current understanding about HPV+OPSCC and clinical differences comparing with HPV−OPSCC including current therapy approaches and describe the clinical importance of determining the HPV status