Open AccessKartagener’s syndrome: A clinical reappraisal with two case reports
Author(s) -
Apoorva Kumar Pandey,
Tripti Maithani,
Aparna Bhardwaj
Publication year - 2014
Publication title -
egyptian journal of ear nose throat and allied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 8
eISSN - 2090-3405
pISSN - 2090-0740
DOI - 10.1016/j.ejenta.2014.06.001
Subject(s) - situs inversus , primary ciliary dyskinesia , bronchiectasis , medicine , kartagener syndrome , chronic sinusitis , infertility , bronchography , sinusitis , cilium , pediatrics , congenital disorder , lung , intensive care medicine , surgery , pregnancy , genetics , biology
Kartagener’s syndrome is a rare congenital disorder consisting of sinusitis, bronchiectasis with situs inversus and is associated with infertility. It is the subgroup of disorder called primary ciliary dyskinesia in which well defined morphological or functional abnormalities of cilia result in sinopulmonary involvement with varying severity. Clinical manifestations involve chronic and/or recurrent respiratory infections with much heterogeneity in multisystem involvement. Early diagnosis and management of this condition help to prevent irreversible lung damage and prevent chronic lifelong sequelae