Open AccessEffect of platelet-rich plasma on nasal mucociliary clearance after submucous diathermy of inferior turbinate
Author(s) -
Ayman H. Salaheldin,
A.C.B. Hussein
Publication year - 2012
Publication title -
egyptian journal of ear nose throat and allied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 8
eISSN - 2090-3405
pISSN - 2090-0740
DOI - 10.1016/j.ejenta.2012.03.003
Subject(s) - medicine , mucociliary clearance , platelet rich plasma , diathermy , saline , surgery , anesthesia , platelet , urology , lung
ObjectiveTo determine the effectiveness of topical application of platelet -rich plasma (PRP) following submucous diathermy (SMD) in promoting the normal ciliary function and improving the healing of nasal turbinate.Patients and methodsThis is a prospective randomized single blinded study done on 60 patients with inferior turbinate hypertrophy (with no or minimal septal deviation). They were divided into 2 groups, study group A consisting of 30 patients who were candidates for bilateral SMD and then PRP was applied; and control group B (30 patients) who were candidates for the same surgery but saline was used instead of PRP. Both groups were followed up after 3days postoperative, then at 1week, 2weeks, one month and 2months consecutively. Nasal mucociliary clearance (NMC) before surgery was assessed (baseline) and was compared to the NMC in the two-week and two-month post operative periods.ResultsNasal mucociliary clearance was improved in both patient groups but it was statistically more significant in group A (with PRP).ConclusionPlatelet-rich plasma has an effective role after submucous diathermy in improvement of nasal mucociliary clearance and decreased incidence of bleeding and crust formation