Open AccessWhat to use for bronchial asthma; nebulized or intravenous magnesium sulfate?
Author(s) -
Ibrahim Salah-Eldin Ibrahim,
Reham Mohamed Elkolaly
Publication year - 2017
Publication title -
egyptian journal of chest diseases and tuberculosis/egyptian journal of chest diseases and tuberculosis
Language(s) - English
Resource type - Journals
eISSN - 2090-9950
pISSN - 0422-7638
DOI - 10.1016/j.ejcdt.2017.01.005
Subject(s) - exacerbation , asthma , medicine , bronchodilator , asthma exacerbations , anesthesia , magnesium , inhalation , materials science , metallurgy
Background: Asthma is characterized by airways narrowing and airflow limitation. The conventional therapy for asthma exacerbation is usually efficient but sometimes patients not respond to it, consequently; other additive drugs may be used as magnesium sulfate(MgSO4) either intravenously or by nebulization.Objective: To compare the bronchodilator effect of MgSO4 via intravenous injection and nebulization in controlling asthma exacerbation.Methods: 40 patients with asthma exacerbation were equally and randomly enrolled in two groups. One group received nebulized MgSO4 (A), and the other group received intravenous MgSO4 (B).Results: Improvement was higher in group B than in group A but without significant change in PEFR also there was no high significant difference in the two group parameters after MgSO4 treatment. Complications were few and manageable in both groups.Conclusion: Intravenous MgSO4 is effective affordable and cheap drug for asthma exacerbation management with good response while nebulized MgSO4 didn’t give the aimed response in these patients