Open AccessIncidence of MRSA infection in pneumonia in cancer patients with phenotyping & genotyping study
Author(s) -
Ahmed A. Khamees,
Nasser M. Abdelbary,
Eman A. El-Masry,
Suzy Gohar
Publication year - 2015
Publication title -
egyptian journal of chest diseases and tuberculosis/egyptian journal of chest diseases and tuberculosis
Language(s) - English
Resource type - Journals
eISSN - 2090-9950
pISSN - 0422-7638
DOI - 10.1016/j.ejcdt.2015.04.013
Subject(s) - medicine , staphylococcus aureus , genotyping , pneumonia , pathogen , cancer , incidence (geometry) , disease , genotype , microbiology and biotechnology , immunology , gene , biology , bacteria , biochemistry , genetics , physics , optics
BackgroundInfections remain a part of the natural course of cancer. During the course of their disease, patients with cancer frequently present with an infection that can ultimately be fatal. Staphylococcus aureus continues to be a dangerous pathogen for both community-acquired as well as hospital-associated infections. S. aureus resistant to methicillin was reported soon after its introduction in October 1960.Material and methodsWe included 40 cancer patients diagnosed with pneumonia, Methicillin resistance test was checked for all isolates of S. aureus. The selected resistance isolates with positive phenotypic tests were subjected to molecular screening study using the PCR amplification technique for detection of mec A gene.Results10 samples of patients isolates were positive for staph infection, 7 out of them are MRSA and confirmed by mec A gene.ConclusionIn any cancer patients with pneumonia that is proved to be caused by staph aureus anti MRSA treatment should be initiated empirically