Open AccessThe effectiveness of non-invasive ventilation in management of respiratory failure in Palestine a prospective observational study
Author(s) -
Baraa Jihad Ibrahim,
Dina Khalid Jaber
Publication year - 2014
Publication title -
egyptian journal of critical care medicine /egyptian journal of critical care medicine
Language(s) - English
Resource type - Journals
eISSN - 2090-9209
pISSN - 2090-7303
DOI - 10.1016/j.ejccm.2014.07.002
Subject(s) - medicine , weaning , observational study , mechanical ventilation , respiratory failure , population , ventilation (architecture) , anesthesia , mechanical engineering , environmental health , engineering
In clinical practice, physicians have recently attempted to avoid mechanical ventilation (MV) as much as possible and have started to use non-invasive ventilation (NIV) in patients with respiratory failure. A prospective observational study was conducted to assess the applicability, effectiveness, and safety of NIV in managing patients with respiratory failure in Palestine. Fifty-two patients (39 patients from West Bank and 13 patients from Gaza Strip) who fulfilled criteria for inclusion were admitted to the two medical care units of the An-Najah National Teaching Hospital during a 10-month period. These patients formed the study population to receive NIV. The results came with baseline (mean±SD) pH, PaO2, and PaCO2 measurements of 7.36±0.1, 75.62±32.7, and 46.5±20.86mmHg, respectively. The primary indication for NIV was hypoxemic respiratory failure (n=38, 73%). The success rate with NIV was 78%, with 40 out of 52 patients weaned successfully. Significant improvements were observed in the first hour following institution of NIV in pH (7.38±0.07, P<0.001), PaO2 (90.4±52.4, P<0.001), and PaCO2 (40.4±12.6, P<0.001). These physiological parameters continued to improve up to the time of weaning: pH (7.39±0.07, P<0.001), PaO2 (99.9±44.3, P<0.001), and PaCO2 (38.6±13.9, P<0.001). The parameters were maintained within 12h post-weaning: pH (7.39±0.08, P<0.001), PaO2 (97±30.3, P<0.001), and PaCO2 (36.9±10.3, P<0.001). This study has shown benefits of NIV in avoiding the call for invasive MV in patients exhibiting respiratory failure of varied etiology, with similar results comparable to previous studies in developed countries. Thus, increased usage of NIV in respiratory failure is likely to affect favorably in countries with limited resources such as Palestine