Open AccessImpact of aortic valve sclerosis on clinical outcome in patients undergoing elective PCI using bare metal stents
Author(s) -
Mohamed Naseem,
Sameh Samir
Publication year - 2015
Publication title -
the egyptian heart journal /the egyptian heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.212
H-Index - 9
eISSN - 2090-911X
pISSN - 1110-2608
DOI - 10.1016/j.ehj.2014.06.002
Subject(s) - medicine , mace , conventional pci , myocardial infarction , percutaneous coronary intervention , cardiology , adverse effect , confidence interval , stent , surgery
BackgroundPrevalence of aortic valve sclerosis (AVS) increases with age. AVS is associated with adverse cardiovascular events. The present study aimed to evaluate the association between AVS and adverse events in patients undergoing elective percutaneous coronary intervention (PCI) using bare metal stents (BMS).MethodsThe study included 200 consecutive patients who underwent elective (PCI) using BMS. Echocardiographic study was done for evaluation of the presence or absence of AVS. Patients were followed for 6months. Major adverse cardiovascular events were defined as cardiac death, acute myocardial infarction (AMI), and stent thrombosis and target lesion revascularization. Total MACE was defined as in hospital and 6-month follow-up MACE.ResultsOf the 200 patients included in the study, 58 patients (29%) were found to have AVS. The presence of AVS was associated with a higher prevalence of cardiovascular risk factors. The total MACE rate was significantly higher in patients with AVS than those with no AVS (44.8% vs. 24.6%, P=0.0082). Using multivariable logistic regression analysis for adjustment of the baseline and echocardiographic characteristics, the association between AVS and adverse events remained significant (odd ratio=0.30; 95% confidence interval, 0.11–0.826).ConclusionAVS is associated with increased morbidity and mortality in patients undergoing elective PCI using BMS