Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis | Zendy

Shiang-Yu Yang | Zendy; ChihHung Lin | Zendy; ChungHsing Chang | Zendy

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Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis

Author(s) -

Shiang-Yu Yang,

ChihHung Lin,

ChungHsing Chang

Publication year - 2017

Publication title -

dermatologica sinica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.604

H-Index - 17

eISSN - 2223-330X

pISSN - 1027-8117

DOI - 10.1016/j.dsi.2017.02.008

Subject(s) - hemophagocytosis , medicine , neutrophilia , dermatology , dermis , erythema , sweet's syndrome , skin biopsy , infiltration (hvac) , papillary dermis , edema , pathology , biopsy , surgery , immunology , bone marrow , physics , pancytopenia , thermodynamics

A 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy revealed exuberant edema of the papillary dermis, extensive neutrophil infiltration, and hemophagocytosis within the dermis. Her symptoms and skin lesions resolved 3 days after initiation of systemic corticosteroids. To the best of our knowledge, this is the first case report of cutaneous hemophagocytosis without additional symptoms of hemophagocytic syndrome in patients with Sweet's syndrome

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