Severe cutaneous thrombosis with hemorrhagic necrosis in a patient with paroxysmal nocturnal hemoglobinuria: A case report and review of literature | Zendy

Fu-Nien Hsieh | Zendy; TsaiYun Chen | Zendy; Julia Yu-Yun Lee | Zendy

Open Access

Severe cutaneous thrombosis with hemorrhagic necrosis in a patient with paroxysmal nocturnal hemoglobinuria: A case report and review of literature

Author(s) -

Fu-Nien Hsieh,

TsaiYun Chen,

Julia Yu-Yun Lee

Publication year - 2017

Publication title -

dermatologica sinica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.604

H-Index - 17

eISSN - 2223-330X

pISSN - 1027-8117

DOI - 10.1016/j.dsi.2017.01.006

Subject(s) - paroxysmal nocturnal hemoglobinuria , medicine , pancytopenia , thrombosis , hemoglobinuria , necrosis , pathology , hemolysis , dermatology , immunology , surgery , bone marrow

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic acquired clonal stem cell disorder, typically manifesting hemolysis, pancytopenia and thrombosis in various organs. PNH-associated cutaneous thrombosis is extremely rare. Herein, we report a case of severe cutaneous thrombosis with hemorrhagic necrosis in a patient with PNH and review the literature

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