Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives | Zendy

Geyang Luo | Zendy; Qian Gao | Zendy; Shuye Zhang | Zendy; Bo Yan | Zendy

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Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives

Author(s) -

Geyang Luo,

Qian Gao,

Shuye Zhang,

Bo Yan

Publication year - 2020

Publication title -

computational and structural biotechnology journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.908

H-Index - 45

ISSN - 2001-0370

DOI - 10.1016/j.csbj.2020.10.016

Subject(s) - computational biology , biology , infectious disease (medical specialty) , rna , disease , medicine , genetics , gene , pathology

The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of various scRNA-seq technologies; primarily discussing the application of scRNA-seq on infectious diseases, and exploring the current development, challenges, and potential applications of scRNA-seq technology in the future.

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