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Kinesin‐driven transport in cell‐free environment
Author(s) -
Böhm Konrad J.
Publication year - 2008
Publication title -
cell biology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 77
eISSN - 1095-8355
pISSN - 1065-6995
DOI - 10.1016/j.cellbi.2007.12.001
Subject(s) - kinesin , microtubule , motility , cytoplasm , microbiology and biotechnology , tubulin , motor protein , chemistry , biophysics , atpase , biology , biochemistry , enzyme
Conventional kinesin is an ATPase‐active motor protein that is involved in the microtubule‐dependent transport of cytoplasmic cargoes. The present paper provides a condensed overview on kinesin‐1 and its motility generation outside a living cell. Moreover, it demonstrates that the neuron‐specific kinesin KIF5A enables the formation of microtubules under conditions where pure tubulin does not assemble.