Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
Author(s) -
Hajera Amatullah,
Isabella Fraschilla,
Sreehaas Digumarthi,
Julie Y. Huang,
Fatemeh Adiliaghdam,
Gracia Bonilla,
Lai Ping Wong,
Marie-Ève Rivard,
Claudine Beauchamp,
Virginie Mercier,
Philippe Goyette,
Ruslan I. Sadreyev,
Robert M. Anthony,
John D. Rioux,
Kate L. Jeffrey
Publication year - 2022
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.06.048
Subject(s) - biology , epigenetics , immune system , chromatin , loss function , bromodomain , genetics , cancer research , microbiology and biotechnology , gene , phenotype
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