Open AccessAPOE told me put my fat in the bag and nobody gets hurt
Author(s) -
Garam Kım,
Aaron D. Gitler
Publication year - 2022
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.05.028
Subject(s) - biology , apolipoprotein e , nobody , disease , gene , genetics , risk factor , cell , bioinformatics , medicine , computer science , operating system
The ε4 variant in the APOE gene is the strongest genetic risk factor for Alzheimer's disease. How does this gene impact different cell types in the brain to increase disease risk? In this issue of Cell, TCW and colleagues report APOE-driven cell-type-specific changes that may contribute to Alzheimer's disease risk.
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