Open AccessCounteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy
Author(s) -
Luciano E. Marasco,
Gwendal Dujardin,
Rui SousaLuís,
Ying Hsiu Liu,
José N. Stigliano,
Tomoki Nomakuchi,
Nicholas Proudfoot,
Adrian R. Krainer,
Alberto R. Kornblihtt
Publication year - 2022
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.04.031
Subject(s) - smn1 , spinal muscular atrophy , biology , exon , snrnp , rna splicing , chromatin , sma* , histone deacetylase , motor neuron , microbiology and biotechnology , gene silencing , histone , cancer research , rna , gene , genetics , neuroscience , spinal cord , mathematics , combinatorics
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