Disrupting autorepression circuitry generates “open-loop lethality” to yield escape-resistant antiviral agents
Author(s) -
Sonali Chaturvedi,
Michael Pablo,
Marie Wolf,
Daniel Rosas-Rivera,
Giuliana Calia,
Arjun J. Kumar,
Noam Vardi,
Kelvin Du,
Joshua Glazier,
Ruian Ke,
Matilda F. Chan,
Alan S. Perelson,
Leor S. Weinberger
Publication year - 2022
Publication title -
cell
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.04.022
Subject(s) - biology , lethality , yield (engineering) , microbiology and biotechnology , synthetic lethality , genetics , mutant , gene , materials science , metallurgy
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