Bacteria in tumors “hit the road” together
Author(s) -
Gregory D. Longmore
Publication year - 2022
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.03.013
Subject(s) - biology , bacteria , breast tumor , metastasis , tumor cells , microbiology and biotechnology , cancer research , breast cancer , genetics , cancer
Tumors contain bacteria, but the functional significance of this tumor microbiota is not appreciated. Fu et al. show that bacteria within breast tumor cells contribute to metastasis, in part, by enhancing tumor cell survival to mechanical fluid shear stress as would be found in the circulation.
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