Roll out the barrel! Outer membrane tension resolves an unexpected folding intermediate | Zendy

Jim E. Horne | Zendy; Sheena E. Radford | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Roll out the barrel! Outer membrane tension resolves an unexpected folding intermediate

Author(s) -

Jim E. Horne,

Sheena E. Radford

Publication year - 2022

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2022.03.001

Subject(s) - biology , folding (dsp implementation) , barrel (horology) , tension (geology) , biophysics , bacterial outer membrane , protein folding , membrane , microbiology and biotechnology , biochemistry , classical mechanics , materials science , physics , structural engineering , moment (physics) , escherichia coli , gene , engineering , composite material

How do bacteria assemble transmembrane β-barrels into their outer membrane in the absence of an energy source? New structures and experiments from Doyle et al. suggest that the β-barrel assembly machinery (BAM) co-opts the power of membrane elastic tension to help complete the folding of β-barrel outer membrane proteins.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research