Fungal sugars boost vaccine protection
Author(s) -
Michail S. Lionakis
Publication year - 2022
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.01.020
Subject(s) - biology , immunogenicity , immune system , glycoprotein , acquired immune system , immunology , innate immune system , virology , biochemistry
In this issue of Cell, Borriello et al. show that soluble fungal mannans elicit potent innate immune responses within skin-draining lymph nodes. These can be exploited for effective development of adaptive immune responses against viral glycoproteins, thus enhancing vaccine immunogenicity and protection.
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