Open AccessIlluminating the path to DNA repair
Author(s) -
Darshana Gupta,
Chase L. Beisel
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.10.005
Subject(s) - biology , genome editing , leverage (statistics) , dna repair , computational biology , genetics , genome , dna , gene , computer science , machine learning
Diverse DNA repair pathways correct ranging types of damage and play central roles in genome editing. In this issue of Cell, two publications leverage a new high-throughput screen that links pathway genes with the outcomes of repair, yielding mechanistic insights into the repair process as well as means to shape editing outcomes.
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