Open AccessMicrobiota regulates intratumoral monocytes to promote anti-tumor immune responses
Author(s) -
Kathy D. McCoy,
Markus B. Geuking
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.09.024
Subject(s) - biology , immune system , tumor microenvironment , gut flora , innate immune system , immunology , cancer , acquired immune system , cancer research , genetics
The gut microbiota has been shown to promote the efficacy of cancer therapy through regulating adaptive immune responses. In this issue of Cell, Lam et al. provide new evidence demonstrating that specific gut bacteria also reprogram the innate immune tumor microenvironment to enhance the efficacy of cancer therapies.
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