Selfish centromeres, selfless heterochromatin
Author(s) -
Elvira Nikalayevich,
MarieHélène Verlhac
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.08.027
Subject(s) - centromere , biology , dicentric chromosome , genetics , chromosome segregation , meiosis , chromosome , heterochromatin , cell division , karyotype , cell , gene
Centromeres are specialized regions on chromosomes recruiting a set of proteins required for faithful chromosome segregation. Differences in centromere strength can potentially bias chromosome segregation toward one of the daughter cells during division. Kumon et al. propose a new model of evolutionary impact on the balance of centromere strength.
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