Open AccessHow the discovery of microbial opsins led to the development of optogenetics
Author(s) -
Jeffrey M. Friedman
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.08.022
Subject(s) - biology , optogenetics , opsin , computational biology , evolutionary biology , neuroscience , genetics , rhodopsin , biochemistry , retinal
This year's Lasker Award recognizes Dieter Oesterhelt, Peter Hegemann, and Karl Deisseroth for their discovery of microbial opsins as light-activated ion conductors and the development of optogenetics using these proteins to regulate neural activity in awake, behaving animals. Optogenetics has revolutionized neuroscience and transformed our understanding of brain function.
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