Open AccessFirst come, first served: Mammalian recombination is timed to replication
Author(s) -
Jason A. Halliwell,
Eva R. Hoffmann
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.07.014
Subject(s) - biology , recombination , replication (statistics) , genetics , dna replication , evolutionary biology , dna , gene , virology
Meiotic recombination drives the formation of new chromosomes in germ cells and is essential for fertility in mammals. In this issue of Cell, Pratto et al. have developed a method to map replication origins directly in mammalian tissue for the first time, revealing evolutionary conservation between replication timing and meiotic recombination in males.
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