Open AccessBacteria make T cell memories in utero
Author(s) -
Elaine L. Parker,
Rachel B. Silverstein,
Indira U. Mysorekar
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.05.044
Subject(s) - biology , in utero , bacteria , immune system , immunology , t cell , cell , fetus , microbiology and biotechnology , neuroscience , genetics , pregnancy
Education of the human immune system begins in utero via T cell activation and memory development. However, whether part of the education is provided by exposure to microbes in utero remains controversial and unclear. In this issue of Cell, Mishra et al. provide new evidence that the fetal gut may be colonized by bacteria that prime T cell memories.
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