Open AccessChanneling plant immunity
Author(s) -
Bruno Pok Man Ngou,
Pingtao Ding,
Jonathan D. G. Jones
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.05.035
Subject(s) - biology , effector , innate immune system , microbiology and biotechnology , immune system , immunity , t cell , intracellular , pathogen , immune receptor , immunology
Plant intracellular NLR proteins detect pathogen effectors and then form multimeric protein complexes ("resistosomes") that activate immune responses and cell death through unknown mechanisms. In this issue of Cell, Bi et al. show that the ZAR1 resistosome exhibits cation channel activity, enabling calcium influx that activates defense mechanisms and culminates in cell death.
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