Open AccessSARS-CoV-2 RNA: Exclusive friends and common foes
Author(s) -
Emmanuelle V. LeBlanc,
Che C. Colpitts
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.04.009
Subject(s) - biology , rna , virology , covid-19 , genetics , gene , outbreak , medicine , disease , pathology , infectious disease (medical specialty)
Infection with SARS-CoV-2 sets off a molecular arms race between virus replication and host cell defense. In this issue of Cell, Flynn, Belk, et al. integrate an advanced large-scale RNA-centered approach with custom CRISPR screens to functionally characterize the interactome of the SARS-CoV-2 RNA genome during infection.
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