Alzheimer’s-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions
Author(s) -
María Szaruga,
Bogdan Munteanu,
Sam Lismont,
Sarah Veugelen,
Katrien Horré,
Marc Mercken,
Takaomi C. Saido,
Natalie S. Ryan,
Tatjana De Vos,
Savvas N. Savvides,
Rodrigo Gallardo,
Joost Schymkowitz,
Frédéric Rousseau,
Nick C. Fox,
Carsten Hopf,
Bart De Strooper,
Lucía ChávezGutiérrez
Publication year - 2021
Publication title -
cell
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2021.03.058
Subject(s) - psen1 , presenilin , amyloid precursor protein , mutant , biology , amyloid (mycology) , mutation , amyloid precursor protein secretase , confusion , alzheimer's disease , microbiology and biotechnology , genetics , disease , gene , psychology , medicine , botany , psychoanalysis
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