Ion channel auxiliary subunit: does one size fit all? | Zendy

Izhar Karbat | Zendy; Eitan Reuveny | Zendy

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Ion channel auxiliary subunit: does one size fit all?

Author(s) -

Izhar Karbat,

Eitan Reuveny

Publication year - 2021

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2020.12.038

Subject(s) - xenopus , polyspermy , biology , ion channel , gating , context (archaeology) , protein subunit , membrane potential , depolarization , sperm , biophysics , microbiology and biotechnology , voltage gated ion channel , oocyte , biochemistry , genetics , embryo , gene , paleontology , receptor

Ion channels can tailor their activity to the particular cellular context by incorporating auxiliary subunits that are channel-type specific. In this issue of Cell, Ávalos Prado et al. now find that a well-characterized voltage-gated K + channel auxiliary subunit can also modulate the gating of Ca 2+ -activated Cl - channels.

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