Open AccessBasophils add fuel to the flame of eczema itch
Author(s) -
Sonali S. Mali,
Diana M. Bautista
Publication year - 2021
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.12.035
Subject(s) - atopic dermatitis , biology , immunology , allergen , dermatology , sensory system , allergy , neuroscience , medicine
Children and adults with atopic dermatitis suffer from intractable chronic itch and can also experience acute itch flare ups that significantly increase itch intensity. In this issue of Cell, Wang et al. demonstrate that a subset of basophils activates sensory neurons to drive allergen-evoked itch flare ups in atopic dermatitis.
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