“Structuromics”: another step toward a holistic view of the cell | Zendy

Emmanuel D. Levy | Zendy; Christine Vogel | Zendy

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“Structuromics”: another step toward a holistic view of the cell

Author(s) -

Emmanuel D. Levy,

Christine Vogel

Publication year - 2021

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2020.12.030

Subject(s) - biology , proteome , computational biology , proteomics , function (biology) , intrinsically disordered proteins , adaptation (eye) , systems biology , protein–protein interaction , structural genomics , protein structure , microbiology and biotechnology , bioinformatics , genetics , neuroscience , biochemistry , gene

Large-scale mapping of protein structures and their different states is crucial for gaining a mechanistic understanding of proteome function and regulation. In this issue of Cell, Cappelletti et al. achieve such a feat and identify hundreds of protein structural changes in response to outside stressors, providing a rich "structuromics" resource characterizing cellular adaptation.

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