Open AccessFighting for Fat: Gluttonous Tumors and Starved T Cells
Author(s) -
Joshua Goodman,
Anthony W. Ferrante
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.11.039
Subject(s) - obesity , cancer , overweight , tumor microenvironment , insulin resistance , biology , cancer research , medicine , carcinogenesis , oncology , endocrinology
In this issue of Cell, Ringel et al. reveal a link between lipid utilization in the tumor microenvironment and anti-tumor immunity in obese mice. These findings provide one explanation for how obesity worsens cancer outcomes and may point to a new metabolic approach to treating some cancers.
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