Open AccessWhen Gut Microbiota Creep into Fat, the Fat Creeps Back
Author(s) -
Sean P. Spencer,
Justin L. Sonnenburg
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.10.008
Subject(s) - biology , gut flora , adipose tissue , bacteria , microbiology and biotechnology , gastrointestinal tract , immunology , genetics , biochemistry
Ha and colleagues describe a previously unappreciated diversity of microbes in the mesenteric adipose tissue (MAT) surrounding the GI tract. Viable bacteria that are mislocalized from the gut microbiota and metabolically adapted to the MAT contribute to the "creeping fat" of Crohn's disease.
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