Open AccessSnapShot: APC/T Cell Immune Checkpoints
Author(s) -
Scott H. Shrager,
Christina Kiel
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.10.007
Subject(s) - snapshot (computer storage) , biology , immune system , immune tolerance , download , antigen , immunology , computational biology , computer science , database , operating system
Immune checkpoints are key regulatory mechanisms integral to the maintenance of self-tolerance and execution of antigen-specific immune responses. In recent years, they have been leveraged to treat both autoimmune disease and various forms of cancer with much success. This SnapShot illustrates known immune checkpoint interactions in APC-mediated T cell modulation. To view this SnapShot, open or download the PDF.
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