SnapShot: The Regulatory Genome
Author(s) -
Xinyang Bing,
Philippe Batut,
Michal Levo,
Michael Levine,
João Raimundo
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.07.041
Subject(s) - biology , snapshot (computer storage) , enhancer , genome , genetics , gene , computational biology , regulatory sequence , regulation of gene expression , gene expression , computer science , operating system
Enhancers switch genes on and off in response to a variety of intrinsic and external cellular signals. They are the cornerstone of gene regulation and the most pervasive constituents of the regulatory genome. Sequence polymorphisms in enhancer DNAs are a major source of population diversity and predilection to disease. To view this SnapShot, open or download the PDF.
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