SnapShot: β-Arrestin Functions
Author(s) -
Seungkirl Ahn,
Sudha K. Shenoy,
Louis M. Luttrell,
Robert J. Lefkowitz
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.07.034
Subject(s) - biology , signal transducing adaptor protein , arrestin , transmembrane protein , microbiology and biotechnology , g protein coupled receptor , repertoire , receptor , transmembrane domain , signal transduction , computational biology , genetics , physics , acoustics
The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transmembrane G protein-coupled receptors. While originally discovered as proteins that block receptor-G protein coupling, arrestins are now appreciated for their expanding repertoire of dynamic protein interactions and cellular functions.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom