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SnapShot: β-Arrestin Functions
Author(s) -
Seungkirl Ahn,
Sudha K. Shenoy,
Louis M. Luttrell,
Robert J. Lefkowitz
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.07.034
Subject(s) - biology , signal transducing adaptor protein , arrestin , transmembrane protein , microbiology and biotechnology , g protein coupled receptor , repertoire , receptor , transmembrane domain , signal transduction , computational biology , genetics , physics , acoustics
The arrestins are ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered by the 7-transmembrane G protein-coupled receptors. While originally discovered as proteins that block receptor-G protein coupling, arrestins are now appreciated for their expanding repertoire of dynamic protein interactions and cellular functions.

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