Open AccessMapping the Uncharted Territories of Human Brain Malignancies
Author(s) -
Daan J. Kloosterman,
Leila Akkari
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.06.003
Subject(s) - immunotherapy , tumor microenvironment , brain cancer , cancer , immune system , biology , brain tumor , cancer immunotherapy , t cell , cancer research , neuroscience , immunology , medicine , pathology , genetics
Despite its success in multiple tumor types, immunotherapy remains poorly efficacious in brain malignancies. In this issue of Cell, Friebel et al. and Klemm et al. provide in-depth insights into the versatile nuances of immune cells in primary and metastatic brain tumors, granting the field with a rich framework to explore novel therapeutic avenues.
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