Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases | Zendy

Lars Fugger | Zendy; Lise T. Jensen | Zendy; Jamie Rossjohn | Zendy

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Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases

Author(s) -

Lars Fugger,

Lise T. Jensen,

Jamie Rossjohn

Publication year - 2020

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2020.03.007

Subject(s) - biology , disease , intensive care medicine , autoimmune disease , immunology , intervention (counseling) , medicine , antibody , pathology , psychiatry

Autoimmune diseases are a result of the immune system being misdirected toward its host and have major and increasing unmet clinical needs. In general, present therapies are broadly acting and non-disease specific; consequently, they are associated with numerous side effects. Precise and early intervention strategies are urgently needed. We highlight the challenges, progress, and prospects in achieving these goals.

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