Snapshot: Trial Types in Precision Medicine | Zendy

Dane J. Dickson | Zendy; Jennifer M. Johnson | Zendy; Raymond C. Bergan | Zendy; Rebecca Owens | Zendy; Vivek Subbiah | Zendy; Razelle Kurzrock | Zendy

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Snapshot: Trial Types in Precision Medicine

Author(s) -

Dane J. Dickson,

Jennifer M. Johnson,

Raymond C. Bergan,

Rebecca Owens,

Vivek Subbiah,

Razelle Kurzrock

Publication year - 2020

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2020.02.032

Subject(s) - snapshot (computer storage) , data collection , observational study , biology , medical physics , data quality , personalized medicine , data science , strengths and weaknesses , clinical trial , computer science , computational biology , bioinformatics , pathology , statistics , database , medicine , engineering , metric (unit) , operations management , philosophy , mathematics , epistemology

Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but narrowly focused. Real-world data (RWD) provide broader information but with variable quality. Master protocols allow better efficiency in data collection. The master observational trial bridges the gap between interventional and retrospective RWD collection methods. To view this SnapShot, open or download the PDF.

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