SnapShot: Natural Killer Cells
Author(s) -
Adeline Crinier,
Émilie Narni-Mancinelli,
Sophie Ugolini,
Éric Vivier
Publication year - 2020
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2020.02.029
Subject(s) - biology , chemokine , innate lymphoid cell , cytotoxic t cell , innate immune system , immunology , secretion , immunity , snapshot (computer storage) , cancer research , microbiology and biotechnology , immune system , genetics , in vitro , biochemistry , computer science , operating system
NK cells are broadly distributed innate lymphoid cells (ILCs) encompassing distinct populations based on CD11b and CD27 expression in mice or CD56 intensity in humans. Involved in anti-viral and anti-tumor immunity thanks to their cytokines and chemokines secretion as well as their cytotoxic capabilities, NK cells have emerged as a promising therapeutic target in several solid tumors and hematological malignancies. To view this Snapshot, open or download the PDF.
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